81| Neuropsych Bite: Clinical Case 3 (Adult, Thalamic Stroke) – Dr. John Bellone

In Clinical Case 3, John presents a neuropsychological evaluation of a woman in her 50s with a left anterior thalamic stroke.

A pdf of the transcript for this episode is available here.

Topics Covered

  • Expected cognitive profile of an anterior thalamic stroke
  • Papez circuit and neuroanatomy involved in memory consolidation
  • Diaschisis/disconnection syndrome
  • Recovery timeline and trajectory following stroke
  • Return to work considerations for stroke patients and some recommendations

Correction to this episode: The pronunciation of “Papez” is likely “pop-esh” given that the name is of Czech origin.

Selected References

Ghika‐Schmid, F., & Bogousslavsky, J. (2000). The acute behavioral syndrome of anterior thalamic infarction: a prospective study of 12 cases. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society, 48(2), 220-227.

Kim, M. H., Hong, S. B., & Roh, J. K. (1994). Amnesia syndrome following left anterior thalamic infarction; with intrahemispheric and crossed cerebro-cerebellar diaschisis on brain SPECT. Journal of Korean medical science, 9(5), 427-431.

Nishio, Y., Hashimoto, M., Ishii, K., Ito, D., Mugikura, S., Takahashi, S., & Mori, E. (2014). Multiple thalamo-cortical disconnections in anterior thalamic infarction: implications for thalamic mechanisms of memory and language. Neuropsychologia, 53, 264-273.

Nishio, Y., Hashimoto, M., Ishii, K., & Mori, E. (2011). Neuroanatomy of a neurobehavioral disturbance in the left anterior thalamic infarction. Journal of Neurology, Neurosurgery & Psychiatry, 82(11), 1195-1200.

Shim, Y. S., Kim, J.-S., Shon, Y. M., Chung, Y.-A., Ahn, K.-J., & Yang, D.-W. (2008). A serial study of regional cerebral blood flow deficits in patients with left anterior thalamic infarction: anatomical and neuropsychological correlates. Journal of the neurological sciences, 266(1-2), 84-91.



  1. You podcast is incredible. I particularly enjoy these case presentations. Thank you!
    Would you provide reference details on the Stucky et al. book and the Russ Bower chapter referred to in this episode please.

    1. Thanks for the feedback Cole! We’re really happy that you’re enjoying these episodes. The book is Clinical Neuropsychology Study Guide and Board Review by Stucky et al. (2020), and Ch. 4 is the functional neuroanatomy chapter by Russ Bauer and Leslie Gaynor that I referred to. Here’s a link to the book on Amazon: https://amzn.to/3kB17GB

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